Mmi1, the Yeast Ortholog of Mammalian Translationally Controlled Tumor Protein (TCTP), Negatively Affects Rapamycin-Induced Autophagy in Post-Diauxic Growth Phase.
Identifieur interne : 000082 ( Main/Exploration ); précédent : 000081; suivant : 000083Mmi1, the Yeast Ortholog of Mammalian Translationally Controlled Tumor Protein (TCTP), Negatively Affects Rapamycin-Induced Autophagy in Post-Diauxic Growth Phase.
Auteurs : Jana Vojtova [République tchèque] ; Jiri Hasek [République tchèque]Source :
- Cells [ 2073-4409 ] ; 2020.
Abstract
Translationally controlled tumor protein (TCTP) is a multifunctional and highly conserved protein from yeast to humans. Recently, its role in non-selective autophagy has been reported with controversial results in mammalian and human cells. Herein we examine the effect of Mmi1, the yeast ortholog of TCTP, on non-selective autophagy in budding yeast Saccharomyces cerevisiae, a well-established model system to monitor autophagy. We induced autophagy by nitrogen starvation or rapamycin addition and measured autophagy by using the Pho8Δ60 and GFP-Atg8 processing assays in WT, mmi1Δ, and in autophagy-deficient strains atg8Δ or atg1Δ. Our results demonstrate that Mmi1 does not affect basal or nitrogen starvation-induced autophagy. However, an increased rapamycin-induced autophagy is detected in mmi1Δ strain when the cells enter the post-diauxic growth phase, and this phenotype can be rescued by inserted wild-type MMI1 gene. Further, the mmi1Δ cells exhibit significantly lower amounts of reactive oxygen species (ROS) in the post-diauxic growth phase compared to WT cells. In summary, our study suggests that Mmi1 negatively affects rapamycin-induced autophagy in the post-diauxic growth phase and supports the role of Mmi1/TCTP as a negative autophagy regulator in eukaryotic cells.
DOI: 10.3390/cells9010138
PubMed: 31936125
PubMed Central: PMC7017036
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Mmi1, the Yeast Ortholog of Mammalian Translationally Controlled Tumor Protein (TCTP), Negatively Affects Rapamycin-Induced Autophagy in Post-Diauxic Growth Phase.</title><author><name sortKey="Vojtova, Jana" sort="Vojtova, Jana" uniqKey="Vojtova J" first="Jana" last="Vojtova">Jana Vojtova</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Microbiology of the Czech Academy of Sciences, Videnska 1083, Prague 4 142 20, Czech Republic.</nlm:affiliation><country xml:lang="fr">République tchèque</country><wicri:regionArea>Institute of Microbiology of the Czech Academy of Sciences, Videnska 1083, Prague 4 142 20</wicri:regionArea><wicri:noRegion>Prague 4 142 20</wicri:noRegion></affiliation></author><author><name sortKey="Hasek, Jiri" sort="Hasek, Jiri" uniqKey="Hasek J" first="Jiri" last="Hasek">Jiri Hasek</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Microbiology of the Czech Academy of Sciences, Videnska 1083, Prague 4 142 20, Czech Republic.</nlm:affiliation><country xml:lang="fr">République tchèque</country><wicri:regionArea>Institute of Microbiology of the Czech Academy of Sciences, Videnska 1083, Prague 4 142 20</wicri:regionArea><wicri:noRegion>Prague 4 142 20</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:31936125</idno><idno type="pmid">31936125</idno><idno type="doi">10.3390/cells9010138</idno><idno type="pmc">PMC7017036</idno><idno type="wicri:Area/Main/Corpus">000134</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000134</idno><idno type="wicri:Area/Main/Curation">000134</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000134</idno><idno type="wicri:Area/Main/Exploration">000134</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Mmi1, the Yeast Ortholog of Mammalian Translationally Controlled Tumor Protein (TCTP), Negatively Affects Rapamycin-Induced Autophagy in Post-Diauxic Growth Phase.</title><author><name sortKey="Vojtova, Jana" sort="Vojtova, Jana" uniqKey="Vojtova J" first="Jana" last="Vojtova">Jana Vojtova</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Microbiology of the Czech Academy of Sciences, Videnska 1083, Prague 4 142 20, Czech Republic.</nlm:affiliation><country xml:lang="fr">République tchèque</country><wicri:regionArea>Institute of Microbiology of the Czech Academy of Sciences, Videnska 1083, Prague 4 142 20</wicri:regionArea><wicri:noRegion>Prague 4 142 20</wicri:noRegion></affiliation></author><author><name sortKey="Hasek, Jiri" sort="Hasek, Jiri" uniqKey="Hasek J" first="Jiri" last="Hasek">Jiri Hasek</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Microbiology of the Czech Academy of Sciences, Videnska 1083, Prague 4 142 20, Czech Republic.</nlm:affiliation><country xml:lang="fr">République tchèque</country><wicri:regionArea>Institute of Microbiology of the Czech Academy of Sciences, Videnska 1083, Prague 4 142 20</wicri:regionArea><wicri:noRegion>Prague 4 142 20</wicri:noRegion></affiliation></author></analytic><series><title level="j">Cells</title><idno type="eISSN">2073-4409</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Translationally controlled tumor protein (TCTP) is a multifunctional and highly conserved protein from yeast to humans. Recently, its role in non-selective autophagy has been reported with controversial results in mammalian and human cells. Herein we examine the effect of Mmi1, the yeast ortholog of TCTP, on non-selective autophagy in budding yeast <i>Saccharomyces cerevisiae</i>, a well-established model system to monitor autophagy. We induced autophagy by nitrogen starvation or rapamycin addition and measured autophagy by using the Pho8Δ60 and GFP-Atg8 processing assays in WT, <i>mmi1Δ</i>, and in autophagy-deficient strains <i>atg8Δ</i> or <i>atg1Δ</i>. Our results demonstrate that Mmi1 does not affect basal or nitrogen starvation-induced autophagy. However, an increased rapamycin-induced autophagy is detected in <i>mmi1Δ</i> strain when the cells enter the post-diauxic growth phase, and this phenotype can be rescued by inserted wild-type <i>MMI1</i> gene. Further, the <i>mmi1Δ</i> cells exhibit significantly lower amounts of reactive oxygen species (ROS) in the post-diauxic growth phase compared to WT cells. In summary, our study suggests that Mmi1 negatively affects rapamycin-induced autophagy in the post-diauxic growth phase and supports the role of Mmi1/TCTP as a negative autophagy regulator in eukaryotic cells.</div></front></TEI><pubmed><MedlineCitation Status="In-Process" Owner="NLM"><PMID Version="1">31936125</PMID><DateRevised><Year>2020</Year><Month>06</Month><Day>11</Day></DateRevised><Article PubModel="Electronic"><Journal><ISSN IssnType="Electronic">2073-4409</ISSN><JournalIssue CitedMedium="Internet"><Volume>9</Volume><Issue>1</Issue><PubDate><Year>2020</Year><Month>01</Month><Day>07</Day></PubDate></JournalIssue><Title>Cells</Title><ISOAbbreviation>Cells</ISOAbbreviation></Journal><ArticleTitle>Mmi1, the Yeast Ortholog of Mammalian Translationally Controlled Tumor Protein (TCTP), Negatively Affects Rapamycin-Induced Autophagy in Post-Diauxic Growth Phase.</ArticleTitle><ELocationID EIdType="pii" ValidYN="Y">E138</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.3390/cells9010138</ELocationID><Abstract><AbstractText>Translationally controlled tumor protein (TCTP) is a multifunctional and highly conserved protein from yeast to humans. Recently, its role in non-selective autophagy has been reported with controversial results in mammalian and human cells. Herein we examine the effect of Mmi1, the yeast ortholog of TCTP, on non-selective autophagy in budding yeast <i>Saccharomyces cerevisiae</i>, a well-established model system to monitor autophagy. We induced autophagy by nitrogen starvation or rapamycin addition and measured autophagy by using the Pho8Δ60 and GFP-Atg8 processing assays in WT, <i>mmi1Δ</i>, and in autophagy-deficient strains <i>atg8Δ</i> or <i>atg1Δ</i>. Our results demonstrate that Mmi1 does not affect basal or nitrogen starvation-induced autophagy. However, an increased rapamycin-induced autophagy is detected in <i>mmi1Δ</i> strain when the cells enter the post-diauxic growth phase, and this phenotype can be rescued by inserted wild-type <i>MMI1</i> gene. Further, the <i>mmi1Δ</i> cells exhibit significantly lower amounts of reactive oxygen species (ROS) in the post-diauxic growth phase compared to WT cells. In summary, our study suggests that Mmi1 negatively affects rapamycin-induced autophagy in the post-diauxic growth phase and supports the role of Mmi1/TCTP as a negative autophagy regulator in eukaryotic cells.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Vojtova</LastName><ForeName>Jana</ForeName><Initials>J</Initials><Identifier Source="ORCID">0000-0003-0174-9331</Identifier><AffiliationInfo><Affiliation>Institute of Microbiology of the Czech Academy of Sciences, Videnska 1083, Prague 4 142 20, Czech Republic.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hasek</LastName><ForeName>Jiri</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Institute of Microbiology of the Czech Academy of Sciences, Videnska 1083, Prague 4 142 20, Czech Republic.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2020</Year><Month>01</Month><Day>07</Day></ArticleDate></Article><MedlineJournalInfo><Country>Switzerland</Country><MedlineTA>Cells</MedlineTA><NlmUniqueID>101600052</NlmUniqueID><ISSNLinking>2073-4409</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="Y">Mmi1</Keyword><Keyword MajorTopicYN="Y">TCTP</Keyword><Keyword MajorTopicYN="Y">autophagy</Keyword><Keyword MajorTopicYN="Y">nitrogen starvation</Keyword><Keyword MajorTopicYN="Y">rapamycin</Keyword><Keyword MajorTopicYN="Y">reactive oxygen species</Keyword><Keyword MajorTopicYN="Y">translationally controlled tumor protein</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2019</Year><Month>11</Month><Day>15</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2019</Year><Month>12</Month><Day>20</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2020</Year><Month>01</Month><Day>03</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2020</Year><Month>1</Month><Day>16</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2020</Year><Month>1</Month><Day>16</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2020</Year><Month>1</Month><Day>16</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>epublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">31936125</ArticleId><ArticleId IdType="pii">cells9010138</ArticleId><ArticleId IdType="doi">10.3390/cells9010138</ArticleId><ArticleId IdType="pmc">PMC7017036</ArticleId></ArticleIdList><ReferenceList><Reference><Citation>Nature. 2007 Feb 15;445(7129):785-8</Citation><ArticleIdList><ArticleId IdType="pubmed">17301792</ArticleId></ArticleIdList></Reference><Reference><Citation>Autophagy. 2017 May 4;13(5):820-833</Citation><ArticleIdList><ArticleId IdType="pubmed">28409693</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Rev Mol Cell Biol. 2009 Jul;10(7):458-67</Citation><ArticleIdList><ArticleId IdType="pubmed">19491929</ArticleId></ArticleIdList></Reference><Reference><Citation>Philos Trans R Soc Lond B Biol Sci. 2010 Mar 12;365(1541):819-30</Citation><ArticleIdList><ArticleId IdType="pubmed">20124347</ArticleId></ArticleIdList></Reference><Reference><Citation>Biochem Biophys Res Commun. 1995 May 5;210(1):126-32</Citation><ArticleIdList><ArticleId IdType="pubmed">7741731</ArticleId></ArticleIdList></Reference><Reference><Citation>FEBS Lett. 2011 Jan 3;585(1):29-35</Citation><ArticleIdList><ArticleId IdType="pubmed">21081126</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS One. 2013 Oct 28;8(10):e77791</Citation><ArticleIdList><ArticleId IdType="pubmed">24204967</ArticleId></ArticleIdList></Reference><Reference><Citation>Methods Enzymol. 2008;451:33-42</Citation><ArticleIdList><ArticleId IdType="pubmed">19185711</ArticleId></ArticleIdList></Reference><Reference><Citation>EMBO J. 2007 Apr 4;26(7):1749-60</Citation><ArticleIdList><ArticleId IdType="pubmed">17347651</ArticleId></ArticleIdList></Reference><Reference><Citation>J Microbiol Biotechnol. 2018 Dec 28;28(12):1982-1991</Citation><ArticleIdList><ArticleId IdType="pubmed">30394045</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 2014 Sep 19;289(38):26554-65</Citation><ArticleIdList><ArticleId IdType="pubmed">25104356</ArticleId></ArticleIdList></Reference><Reference><Citation>Gene. 1997 Jun 19;192(2):245-50</Citation><ArticleIdList><ArticleId IdType="pubmed">9224897</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Rev Mol Cell Biol. 2016 Sep;17(9):537-52</Citation><ArticleIdList><ArticleId IdType="pubmed">27381245</ArticleId></ArticleIdList></Reference><Reference><Citation>FEBS Lett. 1993 Oct 25;333(1-2):169-74</Citation><ArticleIdList><ArticleId IdType="pubmed">8224160</ArticleId></ArticleIdList></Reference><Reference><Citation>BMC Bioinformatics. 2017 Nov 29;18(1):529</Citation><ArticleIdList><ArticleId IdType="pubmed">29187165</ArticleId></ArticleIdList></Reference><Reference><Citation>Cell Signal. 2015 Aug;27(8):1557-68</Citation><ArticleIdList><ArticleId IdType="pubmed">25936523</ArticleId></ArticleIdList></Reference><Reference><Citation>Cell Res. 2014 Jan;24(1):9-23</Citation><ArticleIdList><ArticleId IdType="pubmed">24366340</ArticleId></ArticleIdList></Reference><Reference><Citation>Cell Cycle. 2011 Jan 1;10(1):156-65</Citation><ArticleIdList><ArticleId IdType="pubmed">21191185</ArticleId></ArticleIdList></Reference><Reference><Citation>Cell Death Discov. 2017 Mar 20;3:17016</Citation><ArticleIdList><ArticleId IdType="pubmed">28386457</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Natl Acad Sci U S A. 1981 Sep;78(9):5712-6</Citation><ArticleIdList><ArticleId IdType="pubmed">6946510</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 2001 Dec 14;276(50):47542-9</Citation><ArticleIdList><ArticleId IdType="pubmed">11598139</ArticleId></ArticleIdList></Reference><Reference><Citation>Nature. 2019 Jan;565(7741):606-611</Citation><ArticleIdList><ArticleId IdType="pubmed">30651636</ArticleId></ArticleIdList></Reference><Reference><Citation>Curr Opin Cell Biol. 1997 Dec;9(6):782-7</Citation><ArticleIdList><ArticleId IdType="pubmed">9425342</ArticleId></ArticleIdList></Reference><Reference><Citation>OMICS. 2010 Dec;14(6):629-38</Citation><ArticleIdList><ArticleId IdType="pubmed">20863251</ArticleId></ArticleIdList></Reference><Reference><Citation>Results Probl Cell Differ. 2017;64:69-126</Citation><ArticleIdList><ArticleId IdType="pubmed">29149404</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Cell. 2017 Feb 16;65(4):761-774.e5</Citation><ArticleIdList><ArticleId IdType="pubmed">28132844</ArticleId></ArticleIdList></Reference><Reference><Citation>Autophagy. 2014;10(11):1953-64</Citation><ArticleIdList><ArticleId IdType="pubmed">25483965</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Biol Evol. 2014 Aug;31(8):2194-211</Citation><ArticleIdList><ArticleId IdType="pubmed">24890374</ArticleId></ArticleIdList></Reference><Reference><Citation>Aging Cell. 2013 Aug;12(4):563-73</Citation><ArticleIdList><ArticleId IdType="pubmed">23551936</ArticleId></ArticleIdList></Reference><Reference><Citation>Nucleic Acids Res. 2006 Jan 1;34(Database issue):D535-9</Citation><ArticleIdList><ArticleId IdType="pubmed">16381927</ArticleId></ArticleIdList></Reference><Reference><Citation>Biochim Biophys Acta. 2006 May-Jun;1757(5-6):631-8</Citation><ArticleIdList><ArticleId IdType="pubmed">16806052</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Biol Cell. 2007 Jul;18(7):2525-32</Citation><ArticleIdList><ArticleId IdType="pubmed">17475776</ArticleId></ArticleIdList></Reference><Reference><Citation>Cells. 2017 Jul 13;6(3):</Citation><ArticleIdList><ArticleId IdType="pubmed">28703742</ArticleId></ArticleIdList></Reference><Reference><Citation>Biochem J. 2012 Jan 15;441(2):523-40</Citation><ArticleIdList><ArticleId IdType="pubmed">22187934</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS Biol. 2009 Feb 10;7(2):e38</Citation><ArticleIdList><ArticleId IdType="pubmed">19209957</ArticleId></ArticleIdList></Reference><Reference><Citation>FEMS Yeast Res. 2015 Sep;15(6):</Citation><ArticleIdList><ArticleId IdType="pubmed">26205245</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 1998 Feb 13;273(7):3963-6</Citation><ArticleIdList><ArticleId IdType="pubmed">9461583</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Cell Proteomics. 2015 Sep;14(9):2454-65</Citation><ArticleIdList><ArticleId IdType="pubmed">26077900</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 2010 Jun 4;285(23):17545-55</Citation><ArticleIdList><ArticleId IdType="pubmed">20382742</ArticleId></ArticleIdList></Reference><Reference><Citation>Curr Biol. 2002 Apr 2;12(7):588-93</Citation><ArticleIdList><ArticleId IdType="pubmed">11937029</ArticleId></ArticleIdList></Reference><Reference><Citation>Cell Death Differ. 2005 Nov;12 Suppl 2:1542-52</Citation><ArticleIdList><ArticleId IdType="pubmed">16247502</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Natl Acad Sci U S A. 2006 Oct 10;103(41):15038-43</Citation><ArticleIdList><ArticleId IdType="pubmed">17015830</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Methods. 2014 Mar;11(3):319-24</Citation><ArticleIdList><ArticleId IdType="pubmed">24487582</ArticleId></ArticleIdList></Reference><Reference><Citation>Redox Biol. 2015;4:104-8</Citation><ArticleIdList><ArticleId IdType="pubmed">25545794</ArticleId></ArticleIdList></Reference><Reference><Citation>Microbiol Mol Biol Rev. 2004 Jun;68(2):187-206</Citation><ArticleIdList><ArticleId IdType="pubmed">15187181</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Natl Acad Sci U S A. 2008 Sep 30;105(39):15166-71</Citation><ArticleIdList><ArticleId IdType="pubmed">18812505</ArticleId></ArticleIdList></Reference><Reference><Citation>Cell Div. 2006 Apr 03;1:3</Citation><ArticleIdList><ArticleId IdType="pubmed">16759348</ArticleId></ArticleIdList></Reference><Reference><Citation>Autophagy. 2014 Oct 1;10(10):1702-11</Citation><ArticleIdList><ArticleId IdType="pubmed">25126732</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Biol Cell. 1996 Jan;7(1):25-42</Citation><ArticleIdList><ArticleId IdType="pubmed">8741837</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 2017 Dec 1;292(48):19905-19918</Citation><ArticleIdList><ArticleId IdType="pubmed">29042435</ArticleId></ArticleIdList></Reference><Reference><Citation>Antioxid Redox Signal. 2014 Jan 20;20(3):460-73</Citation><ArticleIdList><ArticleId IdType="pubmed">23725295</ArticleId></ArticleIdList></Reference><Reference><Citation>J Cell Biol. 1992 Oct;119(2):301-11</Citation><ArticleIdList><ArticleId IdType="pubmed">1400575</ArticleId></ArticleIdList></Reference><Reference><Citation>Methods Enzymol. 2008;451:1-26</Citation><ArticleIdList><ArticleId IdType="pubmed">19185709</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 2017 May 19;292(20):8533-8543</Citation><ArticleIdList><ArticleId IdType="pubmed">28320861</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 2019 Apr 5;294(14):5590-5603</Citation><ArticleIdList><ArticleId IdType="pubmed">30755486</ArticleId></ArticleIdList></Reference><Reference><Citation>J Cell Sci. 2012 May 15;125(Pt 10):2349-58</Citation><ArticleIdList><ArticleId IdType="pubmed">22641689</ArticleId></ArticleIdList></Reference><Reference><Citation>EMBO J. 2001 Nov 1;20(21):5971-81</Citation><ArticleIdList><ArticleId IdType="pubmed">11689437</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 2002 Oct 4;277(40):37430-8</Citation><ArticleIdList><ArticleId IdType="pubmed">12149273</ArticleId></ArticleIdList></Reference><Reference><Citation>Cell. 2015 Jun 4;161(6):1413-24</Citation><ArticleIdList><ArticleId IdType="pubmed">26046442</ArticleId></ArticleIdList></Reference><Reference><Citation>Yeast. 1998 Jan 30;14(2):115-32</Citation><ArticleIdList><ArticleId IdType="pubmed">9483801</ArticleId></ArticleIdList></Reference><Reference><Citation>J Vis Exp. 2009 May 06;(27):</Citation><ArticleIdList><ArticleId IdType="pubmed">19421136</ArticleId></ArticleIdList></Reference><Reference><Citation>Biochem Biophys Res Commun. 2005 Dec 30;338(4):1884-9</Citation><ArticleIdList><ArticleId IdType="pubmed">16289106</ArticleId></ArticleIdList></Reference><Reference><Citation>Insect Sci. 2019 Dec;26(6):973-982</Citation><ArticleIdList><ArticleId IdType="pubmed">29316276</ArticleId></ArticleIdList></Reference><Reference><Citation>Cell Death Differ. 2008 Aug;15(8):1211-20</Citation><ArticleIdList><ArticleId IdType="pubmed">18274553</ArticleId></ArticleIdList></Reference><Reference><Citation>Cell Commun Signal. 2018 Nov 20;16(1):85</Citation><ArticleIdList><ArticleId IdType="pubmed">30458881</ArticleId></ArticleIdList></Reference><Reference><Citation>J Cell Biol. 2000 Oct 16;151(2):263-76</Citation><ArticleIdList><ArticleId IdType="pubmed">11038174</ArticleId></ArticleIdList></Reference><Reference><Citation>J Biol Chem. 2009 Mar 20;284(12):8023-32</Citation><ArticleIdList><ArticleId IdType="pubmed">19150980</ArticleId></ArticleIdList></Reference><Reference><Citation>Genes Dev. 2006 May 15;20(10):1294-307</Citation><ArticleIdList><ArticleId IdType="pubmed">16702403</ArticleId></ArticleIdList></Reference></ReferenceList></PubmedData></pubmed><affiliations><list><country><li>République tchèque</li></country></list><tree><country name="République tchèque"><noRegion><name sortKey="Vojtova, Jana" sort="Vojtova, Jana" uniqKey="Vojtova J" first="Jana" last="Vojtova">Jana Vojtova</name></noRegion><name sortKey="Hasek, Jiri" sort="Hasek, Jiri" uniqKey="Hasek J" first="Jiri" last="Hasek">Jiri Hasek</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Bois/explor/RapamycinFungusV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000082 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000082 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Bois
|area= RapamycinFungusV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:31936125
|texte= Mmi1, the Yeast Ortholog of Mammalian Translationally Controlled Tumor Protein (TCTP), Negatively Affects Rapamycin-Induced Autophagy in Post-Diauxic Growth Phase.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:31936125" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a RapamycinFungusV1
| This area was generated with Dilib version V0.6.38. |  |